Another Look at Ecigs

Recently I put up a so-called science article on vaping in which the writers repeated the popcorn lung myth and even went so far as to say, “There is still no definitive answer on whether these risks (of vaping) outweigh the benefits of switching from traditional tobacco cigarettes”. This is despite even the BMA, who were anti ecigs in the beginning, rating them as 99% less harmful than tobacco cigarettes.
Numerous comments ensued, some by those whose lives, and health, have been vastly improved by switching from smoking to vaping, some by those who are against it. I found myself getting irritated by the latter, and somewhat defensive. This of course is not unusual in someone who has used vaping to quit cigarettes. I smoked for about forty years. I took my first puff on a cigarette before I reached my teens and was a full-time smoker by the age of sixteen. I grew up in a society in which smoking was common and allowed just about everywhere. I had heard of course that smoking is bad for you but, as with many, the reality of this did not impinge on me until I felt intimations of mortality in later life. From my 20s to 30s I smoked unfiltered roll-ups but started noticing chest pains, in my 30s to 40s I was using filters but the pains returned. In my late 40s I was delaying the first cigarette of the day with nicotine gum. Throughout all this time I made numerous attempts to quit, on a couple of occasions giving up for as much as a year. I tried NRT and it wasn’t much help. This bears out the statistics on NRT with its dismal quit rate and massive cost to the NHS for each smoker who does quit using by it. By my 50s I had crappy facial skin, frequent eye infections, often used an inhaler to be able to sleep at night and at other times too.
Six or seven years ago Caroline and I had come to the conclusion we had to quit soon – smoking was fucking us up. Out on Crete we saw it in the people around us, with just about every smoker in their 60s facing serious health problems: heart stents and bypasses, emphysema, asthma and of course cancer. Out there Caroline became ill and this gave us a final push and, before heading back to the UK, friends gave us a box of quit smoking items. The usual NRT stuff was in there, but also some early vaporizers. These, when they actually worked, worked very well. Back in the UK I investigated further and discovered a vaping subculture and through that the next generations of vaporizers. Using these more advanced devices we both quit with surprising ease. In my case, within just a few weeks, I no longer needed the inhalers and the pain left my chest. Over further time my skin cleared up and the eye infections all but went away. As I have detailed here before, Caroline died of bowel cancer. Whether that was due to smoking can never be ascertained, but I would say it certainly didn’t help.
On my return to Crete I discovered other changes. My first time swimming again, rather than have to stop after a few hundred yards to catch my breath and cough the debris from my lungs, I swam a straight mile with ease. Also any form of exercise was easier and I did a lot. As a smoker it had almost felt like a pointless pursuit. Vaping had been practically miraculous for me and, in the ensuing years around the world, smoking rates plummeted because of it. But there was a big nasty worm in this apple.
I was utterly baffled by the rise in anti-vaping propaganda. Here was something – a product of small industry – improving and saving people’s lives. I read much of this nonsense: a Daily Mail article screaming about the carcinogens in ecig vapour, it later turning out that the quantity was minimal – no more than in NRT nicotine patches – and below the threshold were any effect could be detected; the panic about diacetyl in ecigs producing popcorn lung, despite the fact that there is more of the stuff in cigarettes and not much in the way of popcorn lung in smokers; ecigs as a ‘gateway’ into smoking for ‘the children’ when all research showed that they did the opposite. Article after article appeared whose sum aim seemed to be to stamp down on, control and even stop an activity that was saving lives. It even became legislation in the EU with the damned Tobacco Products Directive reducing the size of ecig tanks and the strength of their liquids so that they were a lot less effective than they had been. I even began hearing the madness that vaping was worse than smoking. Where was all this coming from?
Crazily a lot of it came from people in the ‘health lobby’. It was almost as if, having spent years singing the ‘quit or die’ mantra and pushing to make cigarettes illegal, they were jealous of something that had turned up from outfield to do a better job than them. Further one can suppose that they were protecting their jobs and inflated salaries. Not so crazily Big Tobacco and drugs companies were against it. The Tobacco Products directive was partially the result of their lobbying of the corporatist (crony capitalist) EU. In both cases this was about sales, in the first sales of cigarettes and in the second the shitloads of money the drugs companies were making from NRT and, if you want to be really cynical, from the medication of smoking related diseases. Governments themselves are also culpable. Ecigs are a disruptive technology and governments are resistant to change, especially when it comes to sources of revenue.
But though the above explains some of the reasons for much of the propaganda it does not fully elucidate it. The ‘fake news’ and such pushes for legislation, control and bans, cannot operate in a vacuum because they need lots of people inclined to believe the first and on board with the rest. Why are many people without financial motives against ecigs? Having had many discussions about this I’ve come to some conclusions.
First off the public has been subject to decades of social engineering – indoctrination – against smoking. Some don’t quite understand how deeply rooted in their minds this is. Some are against ecigs because they cannot see them as different from smoking. A person is breathing in ‘addictive’ nicotine and producing a visible cloud. How is this different from smoking? The simple reality here is that, on the whole, only those who have smoked and quit by using ecigs fully understand the differences. Over years of social engineering people have also been told nicotine is an evil addictive substance. This is a fallacy. Nicotine is only ‘evil’ by association with smoking. By itself it causes little more damage than the addictive substance caffeine. It is the delivery system – the cigarette – that causes the damage with its carcinogens, tar, monoxide, burning leaves and heavy metals. Ecigs don’t do that. ‘But you’re addicted!’ we here the cry, because obviously this is a bad thing. Is it? Why is addiction, per se, a bad thing?
Again this is association. Addiction has, historically, always resulted in damage – to health, to finances, to the mind, whatever. Whenever people hear the word they immediately think of smokers, or someone shoving heroin into their arm, people stoned out of their skulls in rotting tenements, people skull-fucked on cannabis and all the outfall of these. However, if addiction results in none of the above, why is it bad? Quite simply it isn’t. The attitude to addiction is a mind-set, programming, irrational and without thought.
Beyond addiction we come to the vapour an ecig produces. Part of the indoctrination against smoking has been the risible ‘studies’ about the damaging effects of second-hand smoke. These studies have even slid into the Twilight Zone of third-hand smoke. People have been taught to fear it and be disgusted by it, even more than the car fumes that are doing them more damage. To a certain extent I agree with these reactions, but my agreement is limited. Anyone suffering from a lung complaint has reason to abhor cigarette smoke. And they of course have every right to complain. As for the disgust . . . it is only when you stop smoking do you realize how strong it smells and how much it lingers. Is it a bad smell, though? To a minority it always has been, but to the majority it has only become such after being subjected to the aforesaid indoctrination. Very few people thought tobacco smoke was horrible fifty years ago, many in fact liked the whiff of a cigar or a pipe.
Now, when some see ecig vapour, which is little more than flavoured steam with a nicotine quantity that has practically zero effect on them, they react as they have been indoctrinated to react to cigarette smoke. Laughably many of these same people will be going home to put a new cartridge in their plug-in air freshener that does much the same thing as an ecig. Ecig vapour dissipates fast and the biggest ill effect most people will get from it is being subjected to a whiff of caramel or banana. Yet, they will wave their hands and cough dramatically to try and exclude the horrible social pariah who, despite all the evidence, they still think of as a smoker.
But here comes the ‘however’. Though many are reacting as they have been indoctrinated to react to cigarette smoke, there are others whose reaction may be perfectly valid. When I’ve been involved in discussions about this I’ve heard mentioned, with some ire, big clouds of vapour. My own ecig produces a brief waft of vapour that disappears in a few seconds and in some situations I will ‘stealth vape’ i.e. hold the vapour in long enough for it to settle so I breath out nothing visible. But, unfortunately, there are vapers for whom the objective of the practice is not to quell addiction, enjoy a hit of nicotine or the flavour of the liquid they are using, but to produce as large a cloud of vapour as they can manage. When I first saw this, in light of ecig advocates fighting to prevent bans and killing legislation, I felt it was madness. Such a cloud can affect the breathing of others, especially if they have some sensitivity or ailment like asthma, and it can piss off those with none of these.
Here I have to add here that because of the aforesaid indoctrination many are already predisposed to be pissed off, and to have hysterical reactions which could be the root of ill effects. It’s not just the indoctrinated, but quite often ex-smokers. Part of the requirement of many of the latter, in giving up, was learning to hate their habit, and anything remotely like it.
Why do some vapers produce these big clouds? I think it partially relates to the hand waving and dramatic coughing reactions I mentioned above. People can be pushed but only so far, then they push back. The big cloud vapers are probably saying, ‘I can do this here, it’s legal, stop your dramatics and just fuck off.’ There’s a sense of rebellion in it. They were smokers who were turned into pariahs, found a way to stop smoking, only to then discover that some people still classify them as social pariahs, and they’re holding up a middle finger. It’s not clever and it’s not helping along this health revolution, but as we know, whenever a good thing comes along there are always those inclined to screw it up.

Fasting and Fisetin

As far as I understand it fasting has a multitude of benefits beyond just losing weight. You have autophagy and apoptosis, an increase in growth hormone, a reduction in insulin resistance, a reduction through the loss of fat in production of oestrogen and much else besides on the cellular level. You’re also reducing or getting rid of that damaging visceral fat. In fact, many new drugs being developed for dealing with what has been dubbed ‘metabolic syndrome’, i.e. poor lifestyle choices, have effects that are the same as those fasting produces. Psychologically you’re taking control of your body and that, though I hate the word, is empowering.

Combine fasting with exercise and the benefits ramp up. I’ve been fasting now for nigh on two months spending two days a week without food. Also, throughout this time, I’ve been walking longish distances at the weekends and hitting the gym for 50mins three to four times every week. I’m steadily closing on having lost 20lbs of fat, feel light and have better muscle definition, and am feeling pretty good about that. But, as ever, I have to go one step further.

My weight loss has been steadily declining. At the start of this fasting period I was losing (if you discount the large water loss) getting on for 3lbs a week. It’s now down to about half that. I know from my reading that the longer you fast the longer you spend in ketosis and autophagy so the greater benefits you get from them. Because Julie was going away this last weekend I decided to go for a four-day fast and see how I got on with that.

Other reading added something else too. I know that to retard the effects of aging and for good health, weight loss (best through fasting) and exercise are two of the things we as individuals can do. But now another looms on the horizon. A lot, if not most, of the damage of aging comes from senescent cells. These are cells that have malfunctioned but, due to the nature of that malfunction, have not been destroyed by the body. They sit inside us producing SASP – Senescent-Associated Secretory Phenotype – which causes inflammation and has been linked to many disorders. Now studies have shown that by using a senolytic – a drug that causes apoptosis (death) of these malfunctioning cells – one can to a degree reverse some of the effects of aging.

Few senolytics are available. The most effective (in mouse studies) has been a combination of a cancer drug called dasatinib and an over-the-counter supplement called quercetin. The quercetin doesn’t do very much by itself. But there are others that are easily available to us. One is in long pepper – a substance called piperlongumin. Another is fisetin – the flavonoid that gives strawberries their colour. Apparently this last may be best of all and can work without a toxic cancer drug involved. So I decided to use some.

Apparently just a few fisetin capsules don’t have the required senolytic effect. You need to megadose with it, but this stuff supposedly has nothing in the way of adverse side effects. My searches and calculations gave me a dosage of 640mg of pure fisetin (the capsules you buy will have a percentage of fisetin) per day for five days. It is also lipophilic so taking it with an oil of some kind will promote absorption. I raised the dosage to 1000mg a day since I was doing it for four days and not five. The first two days I emptied the capsules into MCT oil and drank it. The stuff tasted foul and after the first two days I could not face it like that so took it in capsule form with fish oil and an MCT/coconut oil coffee on top. That was better.

Now, on the day following all of this, I don’t yet know what effects it has had beyond the immediate effects of the fast itself. The fisetin might not have been sufficiently bioavailable taken by mouth. It might also be the case, as with exercise, that the best results only show up properly after rest and food. Of course I may see nothing at all. Killing off senescent cells does not turn one into superman, but returns one to a previous normal – while the effects of aging are very gradual indeed.

Book Sale Page Three

Okay, please read this post before contacting me. 

The new copies of Polity Agent and Line War below have gone. One and three on the list below.

Details on contact, postage etc are on my first post about these. Scroll down. Also be aware that some of the books in the previous posts have gone. Sorry to disappoint.

I’ll also add here, just on the off-chance, that I have a load of paperbacks of these in German if anyone is interested. Perhaps some Germans read this, or language students, or someone with other connections to that country?

Book Sale Page Two

Contact details and information regarding postage and packing are on the previous post. Unfortunately the uncorrected proof copy of Polity Agent at the bottom here is now gone. I left that on there just so you will know that if you want something, then order it quickly. As on the previous post: first come first served.

Book Sale!

Page One

Mainly so I can keep track I’m going to put these up over a few days. To the prices here I will have to add postage and packing. Dependent on where you are this can amount to as much as if not more than the price of the book. The last time I did this books went missing in the post, so these will have to be either signed for or tracked or both (I haven’t sorted that out yet). If you follow me on Facebook or Twitter you can contact me there, otherwise neallewisasheratgmaildotcom. First come first served. Please don’t ask me about books that do not or have not yet appeared in these posts.

I will sign the books and write in some message as preferred. You’ll also get one of my home made (signed) bookmarks with each purchase.

Hannibal – Netflix Series

I enjoyed this to begin with as it covered the ground of Red Dragon and expanded on it. The lurid murders, convoluted plots and the psychological interplay between the characters satisfied something in my twisted psyche. The camera work was also excellent with some equally satisfying dream sequences. It was of course utterly fantastical but I did not find it an effort to suspend disbelief. But at the back of my mind resided the sure knowledge that the franchise would be extended and the series would probably die, as many do, by stretching an increasingly meagre plot over many episodes. Then along came series two starting out with a sequence from some months in the future that raised my hopes that this would continue to adhere (loosely) to Red Dragon and that it did have a beginning, middle and then end.

The second season started out well with this, but then came an expansion of the psychobabble, the dream sequences and the ‘artistic’ camera work. These last two kinda reminded me of the new Blade Runner film where art forgot story and went wandering off by itself. It even had the same ramping up of the music volume in an attempt to impart meaning where there was none. But I stuck with it because of that initial sequence. In season three it slid into the plot of the film (and book) Hannibal but with its own particular twist on those. Maybe it would have been okay if someone had reined in the ‘artistic filming’ but I suspect someone told them it was really good so they did more of it. The psychobabble also increased to fill the growing void and segued into the nonsensical. The plot was being stretched thin and hardly covered the holes. A few episodes in I finally gave up. Other viewers also gave up because this was not renewed after the third season.

This is, unfortunately, common in many series I see on Netflix. Franchise extending kills them. Film makers should have the courage to propose series that end rather continue sucking at that teat. At best, if they don’t, what starts out as promising turns into soap opera. The money men and executives behind them should also learn from this growing catalogue of failure. I don’t hold out much hope.